This study attempts to explain the correlation between the level of corruption control and vaccination performance across countries, controlling for other important variables related to vaccination. The assumption is that countries with better corruption control are more likely to have better vaccination performance. Secondly, some past studies find that African countries generally performed poorly in vaccination, and form a spatial clustering of poor vaccination performance. It will be a spatial heterogeneous situation. Therefore, this study uses cross-country data to examine the relationship between the level of e-government development and vaccine coverage performance in various countries through traditional regression and geographically weighted regression. The results show that a country's corruption control does positively affect its performance on COVID-19 vaccination. A country with a higher level of corruption control has better vaccine coverage performance. In Africa, the higher the level of corruption control, the higher the improvement in the performance of vaccination compared to other regions in the world.